The Colombian Exchange was good, and bad at the same time. It had it strengths and its weaknesses, but in the end in my opinion I believe it was a good change. I believe that the positive thing was that they were getting many great new resources. By "they" I mean Europe, America, Africa, etc. They also had a great new variety of animals. This helped them a lot.
The negative effects were all the slaves, and the diseases. Just like the Black Death. It wasn't really like the Black Death, but some parts were. For example they had rats on the ships. As a result these rats brought in many sickness to the countries. This all happened on the ships, when they were bringing goods.